BAM-15 50MG / 50 Capsules

Description

DESCRIPTION

BAM-15 50mg Capsules (50 Count) is a small-molecule mitochondrial protonophore (chemical uncoupler) studied in laboratory research models for its action on the inner mitochondrial membrane. Mechanistically, it facilitates the translocation of protons across the membrane, dissipating the electrochemical proton gradient and thereby decoupling electron transport chain activity from ATP synthase. Unlike certain classical uncouplers, BAM-15 is characterized in the literature as acting selectively on the mitochondrial membrane rather than the plasma membrane. This compound is supplied strictly as a reference material for in vitro and non-clinical investigation of cellular bioenergetics and oxidative phosphorylation. Not for ingestion.

RESEARCH AREAS

• Mitochondrial proton gradient dissipation and inner-membrane potential modulation
• Uncoupling of oxidative phosphorylation from electron transport chain flux
• Cellular respiration and oxygen consumption rate dynamics in cultured cells
• Substrate oxidation and metabolic flux pathways in isolated mitochondria

WHAT RESEARCHERS LOOK AT

• Oxygen consumption rate (OCR) profiling via extracellular flux assays
• Mitochondrial membrane potential measurement using fluorescent probe methods
• Dose-dependent uncoupling response and respiratory control ratios
• Membrane selectivity comparisons against reference protonophores in vitro

QUICK SPECS

• Form: Capsule — not for ingestion
• Net per capsule: 50mg
• Count: 50 capsules per bottle
• Purity: ≥98% (HPLC)
• Identity: Confirmed by HPLC/MS
• Storage: Store desiccated at room temperature; protect from light

IDENTITY BASICS

• Type: Small-molecule mitochondrial uncoupler (non-peptide)
• Formula: C16H10F2N6O
• Molecular weight: 364.29 g/mol
• CAS: 364622-82-2

SELECTED RESEARCH

• PubChem CID 6711535 — BAM15 Compound Summary
• PubMed — Identification of a mitochondrial-targeted protonophore (BAM15)
• PubMed — BAM15 and mitochondrial uncoupling in metabolic models
• PubMed — Mitochondrial uncoupler effects on cellular bioenergetics

⚠️ DISCLAIMER

• For laboratory research use only. Not for ingestion.
• Not for human or veterinary use; not for diagnostic or therapeutic application.
• Not a drug, food, or dietary supplement; no medical claims are made.
• Handling restricted to qualified personnel in an appropriate research setting.