In stock
TB 500 Frag 17-23 10mg
$50.00
- Lyophilized synthetic peptide — Thymosin Beta-4 fragment 17-23 (LKKTETQ), 10 mg per vial.
- ≥98% purity (HPLC); identity confirmed by mass spectrometry.
- Intended for in vitro and preclinical laboratory research only.
- Not for human or veterinary use; not a drug or supplement.
Description
DESCRIPTION
TB-500 Frag 17-23 is a synthetic heptapeptide corresponding to the actin-binding domain (residues 17–23, sequence LKKTETQ) of Thymosin Beta-4. In laboratory models this short fragment is studied for its proposed interaction with monomeric G-actin and its potential role in modulating actin polymerization and cytoskeletal sequestration dynamics. It is supplied as a lyophilized research compound for in vitro and preclinical investigation of actin-binding motifs and peptide–protein interaction chemistry. This material is intended strictly for laboratory research purposes and is not a drug, supplement, or article for human or veterinary use.
RESEARCH AREAS
- Actin monomer (G-actin) binding and the LKKTETQ recognition motif
- Modulation of actin filament polymerization and depolymerization kinetics in vitro
- Cytoskeletal sequestration and remodeling pathways in cultured cell models
- Structure–activity relationships of Thymosin Beta-4-derived fragment peptides
WHAT RESEARCHERS LOOK AT
- Binding affinity and stoichiometry against purified G-actin using fluorometric or pyrene-actin assays
- Peptide identity and purity confirmation via HPLC and mass spectrometry
- Reconstitution stability and aggregation behavior under varied buffer conditions
- Comparative motif activity relative to the parent Thymosin Beta-4 sequence in model systems
QUICK SPECS
- Form: Lyophilized powder
- Net per vial: 10 mg
- Purity: ≥98% (HPLC)
- Identity: Confirmed by mass spectrometry
- Storage: Store lyophilized at -20°C; protect from light and moisture
IDENTITY BASICS
- Type: Synthetic heptapeptide fragment (Thymosin Beta-4 17-23)
- Sequence: Leu-Lys-Lys-Thr-Glu-Thr-Gln (LKKTETQ)
- Molecular Formula: C₃₈H₆₈N₁₀O₁₃
- Molecular Weight: ~833.0 g/mol
- CAS: Not formally assigned for the isolated 17-23 fragment
SELECTED RESEARCH
- Thymosin beta-4 and the actin-binding LKKTETQ motif (PubMed)
- Thymosin beta-4 sequesters monomeric G-actin (PubMed)
- Actin-binding domain of beta-thymosins (PubMed)
- LKKTETQ peptide record (PubChem)
⚠️ DISCLAIMER
- For laboratory and research use only — not for human or veterinary use.
- Not a drug, food, supplement, or medical device; no diagnostic or therapeutic use intended.
- Handling restricted to qualified researchers in an appropriate laboratory setting.
- No statements herein have been evaluated by the FDA or any regulatory authority.







