TB-500 (Thymosin Beta-4)

$65.00

Buy exactly 10 units and automatically receive 20% off at checkout.

TB-500 (Thymosin Beta-4) 10mg — synthetic actin-binding peptide for laboratory research.
≥98% purity (HPLC); identity confirmed by mass spectrometry.
Lyophilized powder, 10mg per vial. Store at -20°C.
For laboratory research use only — not for human or veterinary use.

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Description

DESCRIPTION

TB-500 (Thymosin Beta-4) 10mg is a synthetic peptide corresponding to the actin-binding region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid polypeptide. The molecule contains the conserved actin-binding motif (LKKTETQ), which is studied for its capacity to sequester G-actin monomers and modulate actin filament polymerization dynamics within cell-free and cultured-cell model systems. Research interest centers on its interactions with cytoskeletal regulatory pathways and cell-migration signaling at the molecular level. This material is supplied strictly as a reference compound for in vitro and laboratory research.

RESEARCH AREAS

G-actin sequestration and regulation of actin filament assembly kinetics
Cytoskeletal remodeling and cell-motility signaling pathways in cultured cells
Modulation of cell-migration and adhesion mechanisms in vitro
Interactions with extracellular matrix and angiogenesis-related signaling cascades in model systems

WHAT RESEARCHERS LOOK AT

Peptide identity and purity confirmation via HPLC and mass spectrometry
Reconstitution behavior and solution stability under defined buffer conditions
Actin-binding affinity measured through in vitro polymerization assays
Dose-range and time-course parameters in cultured-cell experimental designs

QUICK SPECS

Form: Lyophilized powder
Net per vial: 10mg
Purity: ≥98% (HPLC)
Identity: Confirmed by mass spectrometry
Storage: Store lyophilized at -20°C; protect from light and moisture

IDENTITY BASICS

Type: Synthetic peptide fragment of Thymosin Beta-4 (Tβ4)
Sequence/Formula: Ac-LKKTETQ (actin-binding domain); parent Tβ4 C₂₁₂H₃₅₀N₅₆O₇₈S
Molecular weight: ~4963.4 g/mol (parent Thymosin Beta-4)
CAS: 77591-33-4 (Thymosin Beta-4)

SELECTED RESEARCH

⚠️ DISCLAIMER

For laboratory and in vitro research use only.
Not for human or veterinary use, consumption, or diagnostic application.
Not a drug, food, cosmetic, or therapeutic agent; no medical claims are made.
Handling restricted to qualified research personnel in an appropriate laboratory setting.