L-Glutathione GSH 1500mg

Description

DESCRIPTION

L-Glutathione GSH 1500mg is an endogenous tripeptide composed of L-glutamate, L-cysteine, and glycine, characterized by its reactive sulfhydryl (thiol) group on the cysteine residue. In research models, this thiol moiety participates in redox cycling between reduced (GSH) and oxidized (GSSG) states, serving as a substrate in enzymatic systems involving glutathione peroxidase, glutathione reductase, and glutathione S-transferase.

RESEARCH AREAS

• Thiol-disulfide exchange research — studied for GSH/GSSG redox couple dynamics in cellular buffering models.
• Glutathione enzyme substrate research — investigated for interactions with glutathione peroxidase and reductase systems in vitro.
• Phase II conjugation chemistry — characterized for glutathione S-transferase mediated xenobiotic-handling pathway activity.
• Electrophile-scavenging research — studied for cysteine sulfhydryl reactivity mechanisms at the molecular level.

WHAT RESEARCHERS LOOK AT

• Quantification of GSH:GSSG ratios via spectrophotometric or HPLC assay methods.
• Kinetic characterization of thiol-dependent enzyme reactions in vitro.
• Stability and oxidation profiles of the reduced thiol under varied buffer and pH conditions.
• Conjugate formation and adduct identification by mass spectrometry.

QUICK SPECS

• Form: Lyophilized powder
• Net per vial: 1500 mg
• Purity: ≥98% (HPLC)
• Identity: MS-verified (per COA)
• Storage: -20°C, protect from light and moisture

IDENTITY BASICS

• Type: Tripeptide (γ-L-glutamyl-L-cysteinyl-glycine)
• Formula: C₁₀H₁₇N₃O₆S
• Molecular weight: 307.32 g/mol
• CAS: 70-18-8

SELECTED RESEARCH

• PubChem — chemical identity: https://pubchem.ncbi.nlm.nih.gov/compound/124886
• Glutathione protective roles and biosynthesis: https://pubmed.ncbi.nlm.nih.gov/23434821/
• Glutathione metabolism research: https://pubmed.ncbi.nlm.nih.gov/19514274/
• Glutathione transferase enzymology: https://pubmed.ncbi.nlm.nih.gov/14988435/

Researchers studying redox pathway modulators may also reference NAD+ 500mg for comparative cellular redox research.

⚠️ DISCLAIMER

• This product is intended for laboratory research use only.
• Not for human or veterinary use.
• Not approved for diagnostic, therapeutic, or medical applications.
• Handle using appropriate laboratory safety procedures and personal protective equipment.